Large stone chests are larger versions of the stone chest. Instead of 10 items, large stone chests can hold 50 items. They are as flammable as their predecessor, that is to say, not at all.
You can place stone chests, wooden chests, and their locked counterparts into large stone chests, but this takes up a various amount of item slots, depending on the chest:
Stone chests: 11 item slots
Wooden chests: 9 item slots